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DermaFiller (Bio-Natural Filler)

Cellenis® DermaFiller is a 100% natural injectable material which creates an immediate volumising effect that lasts.

From £



Procedure Time

90-120 min

Risks & Complications

Bleeding, Bruising, Swelling,

Back To WorK

Immediate to Next Day

Recommended Treatment

1-2 sessions








2 weeks

More About:

DermaFiller (Bio-Natural Filler)

Cellenis® DermaFiller is an autologous, biological filler providing extended release of platelet derived growth factors using the slow reabsorption properties of plasmatic proteins. This maintains the renowned efficacy of Cellenis® PRP for a longer time. The patient’s skin will thrive as it induces collagen formation (to create lift), fibrin (to improve texture) and elastin (to enhance elasticity).

The science and technology behind Cellenis® DermaFiller provide a cutting edge, novel technique which adds real volume to the face and body. This is achieved by uniquely heating platelet-poor plasma (PPP) which is rich in albumin. The denaturation and restructure of the proteins provides extended resorption properties lasting up to 3–6 months. During this time, biological activity of Cellenis® DermaFiller enables new tissue formation, providing skin radiance and rejuvenation.

Cellenis® DermaFiller provides the best of two worlds. It combines the superior benefits of Cellenis® PRP tissue regeneration efficacy with the immediate and notable filling effect of a protein scaffold to provide a natural soft-tissue augmentation.

Cellenis® DermaFiller naturally adds volume and lift and rejuvenates the skin.

How Does

DermaFiller (Bio-Natural Filler)


Cellenis® DermaFiller utilizes autologous, biological filler technology, meaning it’s derived from the patient’s own blood components. It releases platelet-derived growth factors slowly, thanks to the reabsorption properties of plasmatic proteins. This sustains the effectiveness of Cellenis® PRP over a longer period. Essentially, it induces collagen formation for lift, fibrin for improved texture, and elastin for enhanced elasticity, resulting in a natural and long-lasting volumizing effect on the skin.

What Can

DermaFiller (Bio-Natural Filler)

Treat ?

Cellenis® DermaFiller can be used to treat various areas of the face and body where volume loss, fine lines, or wrinkles occur. Common treatment areas include:

1. Cheeks: To restore volume and enhance cheek contours.
2. Nasolabial folds: To soften smile lines around the mouth.
3. Marionette lines: To reduce the appearance of downturned corners of the mouth.
4. Lips: To add volume and definition.
5. Jawline: To improve definition and contour.
6. Temples: To replenish lost volume and reduce hollowing.
7. Tear troughs: To minimize the appearance of under-eye hollows.
8. Hands: To rejuvenate and add volume to the backs of the hands.

These are just some examples, and treatment areas can vary depending on individual needs and desired outcomes.

What Does

DermaFiller (Bio-Natural Filler)

Treatment Involve ?

Certainly! The treatment process involves first drawing 11-22ml blood from the patient. This blood is then processed to extract platelet-rich plasma (PRP) using Cellenis® technology. The PRP is further treated by heating it for 10 minutes to create a bio gel. This bio gel is then mixed with the PRP to form the DermaFiller. Finally, the DermaFiller mixture is injected into the chosen areas of the skin to induce collagen formation, improve texture, and enhance elasticity, resulting in a natural and long-lasting volumizing effect.


Unwind and revitalise in our historic and beautiful Castle spa.

Our therapist will listen to your needs and desires and tailor a massage to ensure you leave feeling refreshed, relaxed and rejuvenated.  

With a botanical blissful atmosphere, you will be welcomed with a drink of your choice, every detail will be cared for, you will feel your tension melt away.

All of our massages include luxurious extras which are certain to make them an experience unlike any others.

Our massages are enhanced with the timeless and ancient power of essential oils.

Your therapist will choose the oil specific to you, to intensify the results and your experience.

Feel free to be open and honest with our lovely therapist, to achieve the best outcome for you

You can book a massage alone, or indulge in one of our carefully planned and chosen rituals to make the most out of your visit.

Brows & Lashes

Our lash and eyebrow services are a great introduction to our clinic. A great excuse to come visit the Exeter Castle. Enjoy our range of treatments to fall back in love with your brows and lashes. We cater for all Genders!

All the treatments are performed by our expert spa therapist who has many years of spa and beauty therapist experience.


Whether you’re an experienced client, or new to the world of hair removal, we will take our time to give you quality treatment with excellent results.

Our therapist is professional, friendly and gentle.

With many years experience, working with clients from all backgrounds, all skin types and all nationalities our therapist will ensure you have a satisfying and enjoyable experience.

Luxury Manicure

Basque in the tranquility that is Aesthetica Medical Spa. You will leave feeling relaxed and as special as your are.

Not just a manicure. Sip your bubbly, lie back and relax whilst you enjoy world-renowned brand new luxury nail technology ‘Nails by Mii’ with outstanding service and results. A focus not just on aesthetic but on keeping your hands and nails healthy, supple and strong.

Before & After


Here are some frequently asked questions, cant find an answer? Get in touch and we will be happy to help!

1. What is the difference between Cellenis® DermaFiller and other dermal fillers?

Cellenis® DermaFiller is an autologous, biological filler derived from the patient's own blood components, providing extended release of platelet-derived growth factors. This sustains its efficacy over time compared to synthetic fillers.

Is Cellenis® DermaFiller suitable for all skin types?

Cellenis® DermaFiller is generally suitable for all skin types, but a consultation with a qualified healthcare professional is recommended to determine individual suitability.

How long do the results last?

Results of Cellenis® DermaFiller can last varying lengths depending on individual factors such as metabolism and lifestyle, but typically last between 3 to 6 months.

Are there any side effects associated with Cellenis® DermaFiller?

Side effects of Cellenis® DermaFiller may include temporary redness, swelling, bruising, or tenderness at the injection site. These typically resolve within a few days.

How many sessions of Cellenis® DermaFiller are typically needed to achieve desired results?

The number of sessions needed varies depending on individual needs and desired outcomes, but typically 1 to 3 sessions are recommended for optimal results. You could also repeat this treatment eithe every 4 months or every 6 months to maintain your result.

Can Cellenis® DermaFiller be combined with other cosmetic procedures?

Cellenis® DermaFiller can be combined with other cosmetic procedures such as botulinum toxin injections, mesotherpy or energy treatments for enhanced results.

Is there any downtime associated with Cellenis® DermaFiller treatments?

There is minimal to no downtime associated with Cellenis® DermaFiller treatments, allowing patients to resume their normal activities immediately after the procedure. We aid cellular activation and healing we place you under the dermalux LED therapy light post treatment.

Are the results of Cellenis® DermaFiller immediate, or do they take time to develop?

While some immediate volume enhancement may be visible, the full results of Cellenis® DermaFiller may take a few weeks to fully develop as collagen production is stimulated.

How often should I undergo maintenance treatments with Cellenis® DermaFiller to maintain results?

Maintenance treatments with Cellenis® DermaFiller are typically recommended every 4, 6 or 12 months to maintain optimal results.

More questions? Contact Us

DermaFiller (Bio-Natural Filler)

Price List

DermaFiller (Bio-Natural Filler)
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Related Concerns Treated By: 

DermaFiller (Bio-Natural Filler)

This treatment helps resolve the following concerns

Acne Scarring

Acne scarring results from the healing process of severe acne lesions, leaving visible marks or depressions on the skin. It is quite difficult to treat and will require commitment to a new skin care regimen and full course of treatment.


Mid Face
Cheeks enhancement refers to cosmetic procedures aimed at improving the appearance of the cheeks, addressing concerns such as volume loss, sagging, or asymmetry.


Lower Face
Non-surgical transformative chin enhancement treatments that enhance the chin's projection and contour.

Ageing Hands

Aging hands refer to the visible signs of aging on the hands, including wrinkles, fine lines, volume loss, pigmentation and prominent veins.

Dark Circles

Upper Face
Dark circles, characterised by pigmentation, puffiness and increased vascularity and discoloured skin under the eyes. 

Fine Lines & Wrinkles

Fine lines and wrinkles are natural signs of ageing, caused by a reduction in collagen and elastin production, leading to the loss of skin elasticity. These lines can appear on various areas of the face, including around the eyes, forehead, and mouth.


Lower Face
Jowls refer to the sagging or drooping skin along the jawline, particularly on the lower part of the face

Forehead Lines

Upper Face
Forehead Lines, also known as forehead wrinkles or expression lines, are creases that appear on the forehead due to repetitive facial expressions, ageing, and loss of skin elasticity.

Tear Troughs

Upper Face
Tear Troughs, also known as under-eye hollows or dark circles, refer to the depressions or hollows that can form under the eyes, causing a tired or aged appearance. This condition is often influenced by factors such as genetics, ageing, and volume loss in the under-eye area.

Weak Chin

Lower Face
A weak chin refers to a lack of definition or projection in the lower part of the face, affecting facial harmony and balance. It can be a result of genetic factors, aging, or individual facial structure

Vertical Lip Lines

Lower Face
Vertical lip lines, often referred to as "smoker's lines" or "lipstick lines," are fine lines and wrinkles that appear around the lips, contributing to an aged or worn appearance.

Temple Hollowing

Upper Face
Temple hollowing refers to the loss of volume and a sunken appearance in the temple area of the face. This natural aging process can result in a gaunt and tired look.

Smile Lines (Nasolabial Folds)

Mid Face
Smile lines, also known as nasolabial folds, are the lines that extend from the sides of the nose to the corners of the mouth. These lines become more prominent with age, contributing to an aged or tired appearance.

Skin Rejuvenation

Skin rejuvenation involves a range of advanced treatments aimed at revitalising and enhancing the skin's texture, tone, and overall appearance. This comprehensive approach addresses common concerns such as fine lines, wrinkles, uneven pigmentation, and loss of skin elasticity, promoting a more youthful and radiant complexion.


Pores are small openings in the skin that release oils and sweat. Enlarged pores can be a cosmetic concern, affecting skin texture.

Nose Straightening

Mid Face
Nose Straightening also known as rhinoplasty or non-surgical nose job, is a cosmetic procedure designed to enhance the shape, symmetry, and overall appearance of the nose. At Aesthetica we offer a non-surgical nose job, is a cosmetic procedure designed to enhance the shape, symmetry, and overall appearance of the nose. Whether addressing aesthetic concerns or improving nasal function, this procedure aims to achieve a harmonious and balanced nasal profile.

Marionette Lines

Lower Face
Marionette lines are vertical lines that extend from the corners of the mouth to the chin, creating a puppet-like appearance.

Mid Face Lift

Mid Face
A mid-face lift, also known as a cheek lift, is a cosmetic procedure designed to address sagging or drooping in the mid-face area.

Non-Surgical Facelift

A non-surgical facelift is a rejuvenating procedure designed to lift and tighten facial skin without the need for surgery. This innovative approach utilises non-invasive techniques to address sagging skin, wrinkles, and loss of facial volume, providing a more youthful and refreshed appearance.
Related Treatments

DermaFiller (Bio-Natural Filler)

These are other treatment options that you can consider

Dermal Filler

Dermal Fillers are non-surgical cosmetic enhancements that involve injecting gel-like substances beneath the skin to restore volume, smooth lines, and enhance facial contours.

Hand laser genesis

The 3D-Trilogyice laser is a non-ablative laser system that utilises three different wavelengths to deliver controlled heat deep into the skin's tissue. It can also be employed for certain hand rejuvenation concerns.

HIFU - high-intensity focused ultrasound

Non-Surgical Facelift
3D-Hifu utilizes high-intensity focused ultrasound (HIFU) technology to deliver targeted heat deep within the skin, stimulating collagen production for a non-surgical facelift, wrinkle reduction, and improved skin tone.

Laser Skin Rejuvenation

Laser Skin Rejuvenation with 3D-Trilogyice is a non-invasive procedure using advanced laser technology to address various skin concerns, revitalizing your complexion and revealing smoother, younger-looking skin.

LED Dermalux

LED Dermalux uses specific light wavelengths to energize skin cells, promoting rejuvenation, healing, and addressing various concerns like acne, wrinkles, and pigmentation for a healthy, radiant complexion.

Lip Filler

Enhance your natural lip beauty with lip fillers, a popular injectable treatment using hyaluronic acid to add volume, definition, and a smoother appearance.


Experience a bio-stimulating revolution with Nucleofill, an injectable treatment packed with polynucleotides to deeply renew and rejuvenate your skin, revealing a visibly firmer, smoother, and more radiant complexion.

Non-Surgical Facelift

Non-Surgical Facelift
Looking for a refreshed appearance without surgery? The non-surgical facelift, or liquid facelift/8-point lift, employs strategic dermal filler injections to various facial areas, providing a subtle lift and definition.


Experience long-lasting hydration and rejuvenation with Profhilo®, an innovative injectable treatment using high-purity hyaluronic acid to deeply bio-remodel your skin for visibly smoother, plumper, and younger-looking results.

PRP Platelet Rich Plasma

PRP, or Platelet-Rich Plasma, is a revolutionary treatment using your own concentrated platelets to accelerate healing and rejuvenation in various areas, from skin concerns to sports injuries.


Turn back time on dynamic wrinkles with anti-wrinkle injections, offering a minimally invasive option to soften expression lines and achieve a refreshed, youthful appearance.


Rejuvenate your skin from within with Sunekos, an innovative injectable treatment using a unique blend of hyaluronic acid and amino acids to bio-stimulate collagen and elastin production for a naturally smoother, plumper, and younger-looking complexion.

Light Eyes

A special cocktail containing hyaluronic acid, ruscosides, vitamin C and antioxidants able to improve microcirculation, cutaneous elasticity and drainage in the periocular area.

Online Booking

Use our fast online booking form to book this treatment or consultation

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Contact Aesthetica

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​Exeter Castle Castle Street, Exeter, EX43PU
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